New preclinical research suggests that the traditional Chinese herbal formula, Jinfeng Pills, may help restore endometrial receptivity in cases of thin endometrium, a challenging cause of infertility. In a rat model of endometrial injury, treatment with Jinfeng Pills significantly increased endometrial thickness, improved glandular and vascular density, and restored normal uterine architecture. The effects were accompanied by increased expression of key molecular markers involved in angiogenesis and implantation. Thin endometrium, typically defined as an endometrial thickness of <7 mm, is associated with reduced implantation rates and limited therapeutic options. These findings provide early mechanistic insight into how traditional herbal formulations may support endometrial repair and uterine receptivity, highlighting a potential avenue for integrative approaches in reproductive medicine.

Reference:

Gao H, et al. Reproductive and Developmental Medicine 2025;9(3):149-156. DOI: 10.1097/RD9.0000000000000140.